Subjects received a monochromatic 415 nm blue treatment, or a polychromatic 415 nm and 660 nm treatment. Groups 3 and 4 received cool white light and 5% benzyl peroxide. Patients treated themselves 1x/day for 15 minutes for 12 weeks. At weeks 4 and 8, the red and red-blue groups achieved similar lesion reductions. At week 12, the blue-red group had significantly better results than blue alone. The blue-red group had a 76% inflammatory lesion reduction, significantly higher than the blue light, white light, and benzyl peroxide treatment.
24 mild to severe acne patients with Fitzpatrick skin types II-V received 415 nm blue at one session alternating with 633 nm red at the next. Schedule was 2x/week, 3 days apart, 20 min. per session, 48 J/cm^2 415 nm or 96 J/cm^2 633 nm. All subjects had mild microabrasions before treatment. Both groups saw a 46% lesion count reduction at 4 weeks, and an 81% lesion count reduction at 12 weeks.
Both groups had moderate to severe acne. All subjects received 470 nm blue and 640 nm red light therapy treatments. Group 1 received treatment two times per week for four weeks. At the first weekly session, they received one color treatment. At the second weekly session they received the other color treatment. Group 2 received treatment one time per week. At this session, they first received one color, then they received the second color. Group 1 treatment was spread across two days. Group 2 treatment was delivered in one day. Both groups had significant lesion count reduction, and were not significantly different from one another. Both regimens had significant results.
Randomized Controlled Trial J Eur Acad Dermatol Venereol . 2012 Feb;26(2):219-25. doi: 10.1111/j.1468-3083.2011.04039.x. Epub 2011 Mar 24. Efficacy of blue light vs. red light in the treatment of psoriasis: a double-blind, randomized comparative study M M Kleinpenning 1, M E Otero, P E J van Erp, M J P Gerritsen, P C M van de … Read more
Prospective, Randomized Study on the Efficacy and Safety of Local UV-Free Blue Light Treatment of Eczema Kim Keemss 1, Stephanie C Pfaff, Matthias Born, Jörg Liebmann, Hans F Merk, Verena von Felbert Affiliations expand PMID: 27537360 DOI: 10.1159/000448000 Erratum in Erratum. [No authors listed]Dermatology. 2016;232(4):522. doi: 10.1159/000449445. Epub 2016 Sep 20.PMID: 27648565 No abstract available. Abstract Background: Blue light was shown to reduce the activation of T … Read more