Researchers tested 671 nm and 808 nm 1 mW/cm^2 laser photon delivery in a severed cadaver head. They compared sinus (transsphenoidal), oral, and head (transcranial) light delivery at both wavelengths. 808 delivered more energy than 671 to a 40 mm target inside the brain tissue. They found that sinus delivery delivered 20 times more photons than transcranial delivery. Comparing oral, sinus and head delivery, and comparing 671 nm to 808 nm delivered at the same power density, the 808 nm diode transferred the largest quantity of photons to the farthest parts of the brain.
11 dementia patients received 1060 nm to 1080 nm infrared pulsed at 10 Hz LED treatment for 6 minutes a day for 28 days. They wore a brain helmet irradiating the brain from all directions. Researchers found improved executive functioning, recall, visual attention and task switching, as well as improved EEG amplitude.
89 Alzheimer’s patients received a range of wavelengths in the visible spectrum (25-1000 nm) for 20 to 40 minutes, with continuous or pulsed wave laser. Researchers inserted a fiber optic through a femoral artery catether to deliver light to the cerebral arteries. Analysis showed improved microcirculation, cognitive recovery and decreased dementia.
Two Chronic Traumatic Brain Injury (TBI) patients who also had depression or post trauamtic stress disorder (PTSD) symptoms received 633 nm red and 870 nm transcranial light treatment of 13.3 J/cm^2 10 minutes per site, 1x/weeek for 6 years, or 1x/day for 4 months. Researchers treated bilateral left and right forehead (“and multiple other areas”). At the time of measurement, each had improved executive function, memory and PTSD symptoms.
In a 2013 study researchers irradiated 40 healthy volunteers with 60 J/cm^2 1064 nm continuous laser light for 4 minutes. Targets are 2 unilateral transcranial sites: the right frontal pole on 4 cm medial and lateral. The treated group have improved Psychomotor Vigilance Task reaction time, improved memory task scores and a positive mood when … Read more