Both Low and High Intensity Bright Light Treatment Reduce Epilepsy Correlated Anxiety and Depression

Red light therapy brain dose

Because depression and anxiety have “common psychiatric comorbidities in epilepsy,” researchers tested depression treatment with light on epileptic patients. 101 subjects had “medically intractable focal epilepsy.” Researchers treated 51 subjects with a high-intensity light box, and 50 subjects with a low-intensity light box. Each subject received one treatment per day. Only 58 subjects completed the trial. Depression and anxiety scores were significantly better for both groups. The study included no placebo controls.

810 nm Infrared Transcranial LED Treatment Corresponds with Decreased Depression Scores

Red light therapy brain dose

Ten patients with Major Depressive Disorder (MDD) received 810 nm LED treatment transcranially at 60 J/cm^2. Researchers measured decreased depression and anxiety according to the Hamilton Depression Rating Scale. They did not find changes in cerebral blood flow.

Chronic TBI Infrared Laser Transcranial Treatment

Red light therapy brain dose

10 chronic TBI patients received 810 nm and 980 nm infrared laser treatment of 14.8 to 28.3 J/cm^2 2 to 3 times per week for 8 weeks. Treatments were pulsed at 10 Hz. Transcranial treatment spots included 2 sites on the forehead and 3 bilateral, prefrontal and temporal. At measurement they showed improved headaches, sleep disturbances, cognition, mood regulation,  anxiety and irritability.

Chronic Traumatic Brain Injury, Depression, PTSD, Social Anxiety Transcranial LED Treatment

Red light therapy brain dose

11 chronic traumatic brain injury patients were treated with 633 nm and 870 nm infrared three times per week for six weeks. They received 13 J/cm^2 transcranially on 11 sites at midline and bilateral forehead. At 6 weeks they experience better sleep, decreased PTSD and improved social performance.

Red and Infrared LED Treatment for Traumatic Brain Injury, Depression and PTSD Case Report

Red light therapy brain dose

Two Chronic Traumatic Brain Injury (TBI) patients who also had depression or post trauamtic stress disorder (PTSD) symptoms  received 633 nm red and 870 nm transcranial light treatment of 13.3 J/cm^2 10 minutes per site, 1x/weeek for 6 years, or 1x/day for 4 months. Researchers treated bilateral left and right forehead (“and multiple other areas”).  At the time of measurement, each had improved executive function, memory and PTSD symptoms.

Laser Infrared on Palm Changes Brainwave Amplitude

Red light therapy brain dose

In a 2012 study researchers irradiated 40 healthy volunteers with 830 nm infrared laser light with a dose of 7 mW/diode, 6 diodes, 20 J/cm^2, 10 minutes, pulsed at 10 Hz on the left palm

The treatment increased alpha and theta amplitude in the posterior head region, and decreased beta amplitude in the anterior head region.