Researchers compared “frontal near infrared laser stimulation (N-LT)” [photobiomodulation] with transcranial focused shock wave therapy (F-SWT) on patients with severe disorders of consciousness (DOC). Light therapy subjects received 10 minute infrared sessions of 0.1 mJ/mm2 five times per week for four weeks. A patient in the shock wave group suffered a focal seizure in week 3. Both groups had some members with significant improvements on the revised Coma Recovery Scale (r-CRS), but there were no significant differences between the groups.
A researcher treated a vegatative patient with 850 nm infrared LED 20.5 J/cm^2 for 30 min, 2 times per day, for 73 days. The transcranial treatment included 2 sites at the left and right of the forehead above the eyebrows. At measurement the patient had increased blood flow in the treated area and better neurological outcomes..