This is the EMF Channel database of light therapy study doses. After getting the results, click to view more study details. Only successful studies are included. 99% of the studies here are on humans, not animals. This database is a work in progress. Many thanks to Vlad for his PBM database. When the data here references his work, the detail page includes a link to the PBM spreadsheet.
Red and NIR light dosimetry in the human deep brain
Researchers tested 671 nm and 808 nm 1 mW/cm^2 laser photon delivery in a severed cadaver head. They compared sinus (transsphenoidal), oral, and head (transcranial) light delivery at both wavelengths. 808 delivered more energy than 671 to a 40 mm target inside the brain tissue. They found that sinus delivery delivered 20 times more photons than transcranial delivery. Comparing oral, sinus and head delivery, and comparing 671 nm to 808 nm delivered at the same power density, the 808 nm diode transferred the largest quantity of photons to the farthest parts of the brain.
Significant Gulf War Illness (Chronic Multisymptom Illness) Improvements after 12 Weeks of Vielight Neuro Alpha Treatment
Improvements in Gulf War Illness Symptoms After Near-Infrared
Transcranial and Intranasal Photobiomodulation: Two Case
Researchers tested the effects of the Vielight Neuro Alpha photobiomodulation device on Gulf War Illness (GWI) symptoms. GWI symptoms include persistent headaches, cognitive difficulties, joint pain, musculoskeletal pain, fatigue, gastrointestinal problems. Because the pattern can present in non-Gulf War veterans, the phenomenon is also called Chronic Multisymptom Illness (CMI). A CMI diagnosis is 6 months of symptoms in at least two of these categories: fatigue, pain, and cognitive-mood. A Kansas GWI is moderately severe or multiple chronic symptoms in at least three of these categories: fatigue/sleep problems, pain, neurological/
cognitive/mood problems, respiratory problems, gastrointestinal problems, and skin problems.
Subjects took self-assessment questionnaires and cognitive tests. They tested before treatment and at the 12-week mark. Gulf War Veteran 1 (GWV1) presented as a Kansas GI. Gulf War Veteran 2 (GWV2) presented as Kansas GWI. Subjects used the Vielight Neuro Alpha device daily for 12 weeks. The device delivers:
- 810 nm 100 mW/cm^2 pulsed at 10 Hz to 3 posterior transcranial targets
- 810 nm 75 mW/cm^2 pulsed at 10 Hz to an anterior target
- 810 nm 25 mW/cm^2 pulsed at 10 Hz to an intranasal passage
At 12 weeks both subjects improved on multiple scores. GWV1 no longer qualified as Kansas GWI. He was re-categorized as mild-moderate CMI. GWV1 showed improvements in mood-cognitive, pain, sleep and fatique categories.
GWV2 was re-categorized from severe CMI to mild-moderate CMI. He showed improvements in fatique, pain and mood-cognitive scores.
Changes in Brain Function and Structure After Self-Administered Home Photobiomodulation Treatment in a Concussion Case
One 23-year old traumatic brain injury patient complained of headaches, anxiety, and difficulty concentrating. He home-treated with a Vielight Neuro Duo. At an 8 week measurement he had increased brain volume, improved functional connectivity, increased cerebral perfusion, and neuropsychological improvements.
Improvements in clinical signs of Parkinson’s disease using photobiomodulation: A prospective proof-of-concept study
- Vielight Gamma 4 LEDs, 240 joules, four transcranial targets
- Vielight Gamma 1 LED, 15 joules, one intranasal target
- Irradia MID 2.5 4 Laser Diodes, 39.6 joules, or MIDCARE laser, 2 diodes, 39.6 joules, C1/C2 neck region and abdomen
Group 1 Schedule:
- Weeks 1-4: 3x/week
- Weeks 5-8: 2x/week
- Weeks 9-12: 1x/week
- Weeks 13-40: 3x/week
Group 2 Schedule:
- Weeks 13-25: 3x/week
Groups were tested before and after PBM treatment on measures:
- Functional Mobility task of Time Up and Go (TUG): Stand, walk 3 m, turn, return, sit down
- Gait TUG Motor: First task plus carrying water
- Gait TUG Cognitive: First task plus counting backwards in twos
- Gait TUG 10 Meter Walk: Time to walk 14 meters after having already walked 2 meters
- Gait TUG 10 Meter Stride: Number of strides to walk last 6 m of task above
- Dynamic Balance Step Test: Number of times patient used a step for balance
- Cognition Montreal Cognitive Assessment: Standardized cognition test
- Fine Motor Skills Spiral Test: Drawing within the lines
- Fine Motor Skills Nine Hole Peg: Put pegs in holes, return pegs to bin
- Fine Motor Skills Micrographia: Handwriting area taken per word
- Static Balance Tandem Stance: Duration of standing with one foot ahead of the other
- Static Balance Single Leg Stance: Duration of standing with one foot in the air
Participants in both groups saw significant improvement in functional mobility, dynamic balance, and cognition. Results were good but not significant for fine motor skills and static balance.
Neuroplastic effects of transcranial near-infrared stimulation (tNIRS) on the motor cortex
16 comatose patients received 785 transcranial 785 nm infrared laser treatments five timers a week for four weeks. Post treatment measurement showed improved alertness, and improved awareness over time.
Transcranial 850 nm Infrared Treatment of Vegatative Patient Yields Blood Flow and Neurological Improvement
Focal increase in cerebral blood flow after treatment with near-infrared light to the forehead in a patient in a persistent vegetative state
A researcher treated a vegatative patient with 850 nm infrared LED 20.5 J/cm^2 for 30 min, 2 times per day, for 73 days. The transcranial treatment included 2 sites at the left and right of the forehead above the eyebrows. At measurement the patient had increased blood flow in the treated area and better neurological outcomes..
Transcranial Laser Stimulation as Neuroenhancement for Attention Bias Modification in Adults with Elevated Depression Symptoms
51 patients with elevated depression symptoms received 1064 nm infrared transcranial laser treatments over two sessions. Researchers concluded that “right prefrontal irradiation improved attention bias modification intervention effects and depression symptoms.”
Transcranial 808 nm High Dose Infrared Significantly Improves Major Depressive Disorder Rating Scores
Near-Infrared Transcranial Radiation for Major Depressive Disorder: Proof of Concept Study
4 Major Depressive Disorder (MDD) patients received 808 nm infrared laser treatment at 84 J/cm^2 at 4 sites transcranially. At 6 weeks post irradiation they had healthier Hamilton Depression Rating Scale scores on 17 items.
Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety
Ten patients with Major Depressive Disorder (MDD) received 810 nm LED treatment transcranially at 60 J/cm^2. Researchers measured decreased depression and anxiety according to the Hamilton Depression Rating Scale. They did not find changes in cerebral blood flow.
Vielight 810 and Neuro Intranasal and Transcranial Infrared LED Significantly Decreases Dementia Symptoms
Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report
A 2017 study in Photomedicine and Laser Surgery found improved dementia symptoms after 810 nm infrared transcranial and intranasal irradiation of five patients using Vielight 810 and Neuro LED devices. Patients received 10.65 J/cm2 from 14.2 mW/cm^2 or 24.6+13.8 J/cm^2 from 41+23 mW/cm^2. Treatment times for 25 or 20 minutes. The devices output 10 Hz pulsed wave. The study lasted 12 weeks. Vielight 810 is an intranasal device. The Neuro is transcranial and intranasal. Light reached “bilateral mesial prefrontal cortex, precuneus/posterior cingulate cortex, angular gyrus, and hippocampus.” Results included dementia improvement of sleep, fewer angry outburts, reduced anxiety and reduced wandering.
Photobiomodulation with Near Infrared Light Helmet in a Pilot, Placebo Controlled Clinical Trial in Dementia Patients Testing Memory and Cognition
11 dementia patients received 1060 nm to 1080 nm infrared pulsed at 10 Hz LED treatment for 6 minutes a day for 28 days. They wore a brain helmet irradiating the brain from all directions. Researchers found improved executive functioning, recall, visual attention and task switching, as well as improved EEG amplitude.
Dementia and Cognitive Impairment Reduction after Laser Transcatheter Treatment of Alzheimer’s Disease
89 Alzheimer’s patients received a range of wavelengths in the visible spectrum (25-1000 nm) for 20 to 40 minutes, with continuous or pulsed wave laser. Researchers inserted a fiber optic through a femoral artery catether to deliver light to the cerebral arteries. Analysis showed improved microcirculation, cognitive recovery and decreased dementia.
A new treatment protocol using photobiomodulation and muscle/bone/joint recovery techniques having a dramatic effect on a stroke patient’s recovery: a new weapon for clinicians
A stroke victim received 660 nm and 850 nm irradiation to 32 sites on the head, brainstem, spine and musculature from a 1400 mW device delivering 2.95 J/cm^2. Each site received treatment for 1 minute, 1 time per week for 8 weeks. The author found improvements in cognitive and physical deficits.
Infrared laser therapy for ischemic stroke: a new treatment strategy: results of the NeuroThera Effectiveness and Safety Trial-1 (NEST-1)
120 acute stroke patients received 808 nm transcranial laser within 24 hours of onset. Each received 1.2 J/cm^2 at the cortext for 2 minutes on 20 sites on a shaved scalp. Analysis found improvement based on the NIH Health Stroke Scale, modified.
Transcranial Low-Level Laser Therapy May Improve Alertness and Awareness in Traumatic Brain Injured Subjects with Severe Disorders of Consciousness: a Case Series
Five traumatic brain injury patients with cognitive disabilities received transcranial 785 nm infrared laser 5 times per week for 6 weeks. They showed improved awareness and alertness, but two epileptic fits corresponded with treatment earlier that day. The fits also corresponded with concurrent antibiotic treatments.
Treatments for traumatic brain injury with emphasis on transcranial near-infrared laser phototherapy
10 chronic TBI patients received 810 nm and 980 nm infrared laser treatment of 14.8 to 28.3 J/cm^2 2 to 3 times per week for 8 weeks. Treatments were pulsed at 10 Hz. Transcranial treatment spots included 2 sites on the forehead and 3 bilateral, prefrontal and temporal. At measurement they showed improved headaches, sleep disturbances, cognition, mood regulation, anxiety and irritability.
Significant Improvements in Cognitive Performance Post-Transcranial, Red/Near-Infrared Light-Emitting Diode Treatments in Chronic, Mild Traumatic Brain Injury: Open-Protocol Study
11 chronic traumatic brain injury patients were treated with 633 nm and 870 nm infrared three times per week for six weeks. They received 13 J/cm^2 transcranially on 11 sites at midline and bilateral forehead. At 6 weeks they experience better sleep, decreased PTSD and improved social performance.
Improved Cognitive Function After Transcranial, Light-Emitting Diode Treatments in Chronic, Traumatic Brain Injury: Two Case Reports
Two Chronic Traumatic Brain Injury (TBI) patients who also had depression or post trauamtic stress disorder (PTSD) symptoms received 633 nm red and 870 nm transcranial light treatment of 13.3 J/cm^2 10 minutes per site, 1x/weeek for 6 years, or 1x/day for 4 months. Researchers treated bilateral left and right forehead (“and multiple other areas”). At the time of measurement, each had improved executive function, memory and PTSD symptoms.
Beneficial Effects of Transcranial Light Emitting Diode (LED) Therapy on Attentional Performance: An Experimental Design
39 healthy volunteers received 60 J/cm^2 of 850 nm infrared LED transcranially. They experienced improved attentional performance in the Go/No task.
Acute Effects of Near Infrared Light Therapy on Brain State in Healthy Subjects as Quantified by qEEG Measures
In a 2017 study, 31 healthy volunteers received 903 nm LED LumiWave light transcranially. They experienced improved reaction time in the qEEG event-related response test.
The effects of transcranial LED therapy (TCLT) on cerebral blood flow in the elderly women
In a 2015 study, 25 healthy elderly women received 627 nm LED light transcranially at four sites, two times per week for four weeks. They experienced increased cerebral artery velocity at both systolic and idastolic measurements.
Acute Effects of Near Infrared Light Therapy on Brain State in Healthy Subjects as Quantified by qEEG Measures
Blanco et al. 2017  Healthy volunteers (118) Laser, CG-5000, Cell
Gen Therapeutics, LLC (Dallas, TX, USA) 1064 nm 250 mW/cm2, 60 J/cm2, 8 min, one irradiation session, CW Transcranially;
2 sites, lower and upper portion of right lateral forehead at EEG map sites: FP2, F4, and F8 sites Improved prefrontal rule-based learning; no significant effects on information-integration learning
Transcranial laser stimulation improves human cerebral oxygenation
In a 2016 study 12 healthy volunteers were irradiated with a 1064 nnm laser light dose of 13.75 J/cm^2 per minute for 10 minutes. Light shone on the center forehead and right side. Treated subjects exhibited higher oxygen concentration in hemoglobin across the two hemispheres. Oxygenation increased during treatment and continued at least 6 minutes after.
Improving executive function using transcranial infrared laser stimulation
In a 2015 study 30 healthy volunteers received 60 J/cm^2 1064 nm irradiation on two forehead sites. They showed improved executive function after treatment.
Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans
In a 2013 study researchers irradiated 40 healthy volunteers with 60 J/cm^2 1064 nm continuous laser light for 4 minutes. Targets are 2 unilateral transcranial sites: the right frontal pole on 4 cm medial and lateral. The treated group have improved Psychomotor Vigilance Task reaction time, improved memory task scores and a positive mood when measured 2 weeks after treatment.
Effect of Low-Level Laser Stimulation on EEG
In a 2012 study researchers irradiated 40 healthy volunteers with 830 nm infrared laser light with a dose of 7 mW/diode, 6 diodes, 20 J/cm^2, 10 minutes, pulsed at 10 Hz on the left palm
The treatment increased alpha and theta amplitude in the posterior head region, and decreased beta amplitude in the anterior head region.
Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris
Subjects received a monochromatic 415 nm blue treatment, or a polychromatic 415 nm and 660 nm treatment. Groups 3 and 4 received cool white light and 5% benzyl peroxide. Patients treated themselves 1x/day for 15 minutes for 12 weeks. At weeks 4 and 8, the red and red-blue groups achieved similar lesion reductions. At week 12, the blue-red group had significantly better results than blue alone. The blue-red group had a 76% inflammatory lesion reduction, significantly higher than the blue light, white light, and benzyl peroxide treatment.
In cataloguing this study, the “cool white light” is classified as having “unknown” wavelengths.
Combination blue (415 nm) and red (633 nm) LED phototherapy in the treatment of mild to severe acne vulgaris
24 mild to severe acne patients with Fitzpatrick skin types II-V received 415 nm blue at one session alternating with 633 nm red at the next. Schedule was 2x/week, 3 days apart, 20 min. per session, 48 J/cm^2 415 nm or 96 J/cm^2 633 nm. All subjects had mild microabrasions before treatment. 22 patients were assessed, 2 dropped out. Researchers objectively counted a 46% lesion count reduction at 4 weeks, and an 81% lesion count reduction at 12 weeks.
FLUORESCENT LIGHT ENERGY: The Future for Treating Inflammatory Skin Conditions?
Photodynamic Light Therapy
When applied with a topical substance, light therapy becomes photodynamic therapy (PDT). Kleresca is a photodynamic therapy treatment manufacturer based in Europe and Australia.
Kleresca marketing refers to this process as biophotonics. In home LED therapy, the chromophores in the mitochondria absorb the photons to create an ATP and nitric oxide response. In PDT, the topical substance absorbs the photons. Then, the substance is potentiated to heal, or the absorption transfers photon energy to the skin. In this case, it appears that the chromophore gel is a mediator to get more photons to the skin.
This study looked at the Kleresca chromophore gel’s light absorption properties.
Researchers tested gel penetration of fluorescent light energy (FLE) of 375 nm, 405 nm, 435 nm, 450 nm, 470 nm, 505 nm, 525 nm, 570 nm, 590 nm, 630 nm, 645 nm, 660 nm, 700 nm, 850 nm, 870 nm, 890 nm, 940 nm and 970 nm.
They tested the reflection and absorption qualities of the gel with each color. They found that 375 nm had the highest reflectance. 405 nm through 590 nm had the highest absorption. 630 nm through 970 nm had less but still significant absorption. In other words, at least 5 wavelengths between 405 nm and 590 nm deeply penetrate the chromophore gel; at least nine red and infrared wavelengths significantly penetrate the gel. 375 nm is a high reflectance outlier. The gel maintained fluorescence for up to 15 minutes after exposure.
The fluorescent Kleresca lamp output similar irradiance to an LED analogue. Irradiance for both lamps peaked at just under 10 mW/cm^2 and 435 nm. Irradiance was lowest at 500 nm to 550 nm at .01 mW/cm^2 (LED) and .001 mW/cm^2 (Kleresca). Lamps peaked output again at 570 nm at just under .1 mW/cm^2 and plummeted back to 0.001 between 630 nm and 700 nm.
Authors tested Kleresca PDT on one acne patient. Inflammation reduction peaked at week 20 and corresponded with significant lesion reduction. More acne resolution occurred from week 21 to week 57 with visible reductions at week 33, week 45 and week 57.
A third test compared fibroblast collagen production under LED and Kleresca. Kleresca produced more collagen compared to LED in untreated skin. In part 2 of the collagen test, researchers added interferon inflammatory markers to the fibroblast cells. LED collagen production remained consistent, but FLE dramatically fell below LED results. In the presence of inflammatory marker, LED produced the same collagen, and FLE produced significantly less collagen.
In a confusing statement of conflict, the authors state that they Kleresca employees, but that Kleresca did not fund the study, and there are no conflicts of interest.
A Comparative Study Between Once-Weekly and Alternating Twice-Weekly Regimen Using Blue (470 nm) and Red (640 nm) Light Combination LED Phototherapy for Moderate-to-Severe Acne Vulgaris
Both groups had moderate to severe acne. All subjects received 470 nm blue and 640 nm red light therapy treatments. Group 1 received treatment two times per week for four weeks. At the first weekly session, they received one color treatment. At the second weekly session they received the other color treatment. Group 2 received treatment one time per week. At this session, they first received one color, then they received the second color. Group 1 treatment was spread across two days. Group 2 treatment was delivered in one day. Both groups had significant lesion count reduction, and were not significantly different from one another. Both regimens had significant results.
Efficacy of blue light vs. red light in the treatment of psoriasis: a double-blind, randomized comparative study
Researchers treated psoriasis patients without treating it with any photosensitizers. Protoporphyrin IX (PpIX) is an endogenous photoreceptor. Both 420 nm blue and 630 nm red equally reduced psoriasis symptoms. Blue reduced redness more than red.
Red Light Combined with Blue Light Irradiation Regulates Proliferation and Apoptosis in Skin Keratinocytes in Combination with Low Concentrations of Curcumin
Researchers combined topical curcumin with 405 nm blue light, and then either 630 nm or 660 nm red light. Both treatment groups showed significant decrease in symptoms. The treatments decreased keratinocytes cell proliferation, which is the primary causative factor in psoriasis symptoms.
Prospective, Randomized Study on the Efficacy and Safety of Local UV-Free Blue Light Treatment of Eczema
21 patients with mild to moderate eczema were treated with LED 453 nm 3x/week for 4 weeks. All patients had statistically significant improvements on the Eczema Severity Index (ESI).
Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes
Researched irradiated human fat with 410 nm, 457 nm, 505 nm, 530 nm, 590 nm, and 660 nm low level light. 590 nm “significantly reduced the concentration of lipid droplets” and increased lipid autophagy (broke down fat). In documenting the science of photobiomodulation, I rarely come across a study that finds significant effect at one wavelength, and no effect at nearby wavelengths. That did happen in this study. 590 nm affected fat breakdown and 505 nm did not. The abstract did not mention the other wavelengths tested. Presumably they were also insignificant, so it’s unclear why 505 nm was singled out as ineffective.
Low-Level Light Therapy Downregulates Scalp Inflammatory Biomarkers in Men With Androgenetic Alopecia and Boosts Minoxidil 2% to Bring a Sustainable Hair Regrowth Activity
Researchers tested low level light therapy to see if it would reduce scalp inflammation that interferes with hair re-growth. They tested the L’Oréal LLLT/GentleWaves® device’s effect on hair growth. 64 men with androgenetic alopecia received 590 nm for 70 seconds (pulsed) 1x/day for 3 days. Their scalps were DNA squenced. Then they tested the device as well as Minoxidil on 135 men and women with alopecia. The 590 nm treatment correlated with downregulation of sclap inflammatory biomarkers in half the treated subjects. The second study showed increase Minoxidil hair growth. Those receiving 2% Minoxidil responded as if they had received 5% Minoxidil.
Photobiomodulation reduces drusen volume and improves visual acuity and contrast sensitivity in dry age-related macular degeneration
Researchers treated 42 eyes with 590 nm, 670 nm and 790 nm LED light over 3 weeks. Patients experienced improved scores on “best-corrected visual acuity (BCVA), contrast sensitivity (CS), drusen volume and central drusen thickness” at either 3 week or 3 month testing.
Prevention of Thyroidectomy Scars in Asian Adults With Low-Level Light Therapy
Researchers treated 35 thyroidectomy patients with a combination of 830 nm and 590 nm LED light. Patients received 60 J/cm over a period of 11 minutes for 7 days, starting on the day of surgery. After the first week, they received treatment 3x/week for 3 more weeks. At 3 months, scars on treated patients were lighter and had less color compared to controls. Self-assessment of scar was not significantly different between treated and control groups.
A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings
76 patients received split face LED treatment with 830 nm, 633 nm, or a combination of 830 nm and 633 nm. The control group received a sham treatment. Patients received therapy twice a week for four weeks. Measuring skin elasticity and melanin revealed wrinkle reduction as high as 36% and up to 19% skin elacity increase. Researchers concluded that 830 and 633nm alone and in combination are effective wrinkle reducing wavelengths.
The Efficacy and Safety of 660 nm and 411 to 777 nm Light-Emitting Devices for Treating Wrinkles
Researchers treated subjects with LED therapy the specific wavelength 660 nm (red for group 1) and a range of wavelengths from 411 to 777 nm (white for group 2). 52 women received 5.17 J daily for 12 weeks. Wrinkles significantly improved (reduced). Group 1 had slightly better results, but the differences were not significant.
Prospective randomized study on the efficacy of blue light in the treatment of psoriasis vulgaris
Forty patients self-treated with 420 nm blue LED light therapy once a day for four weeks. 20 patients self-treated with 453 nm blue LED in parallel. Both groups should statistically substantial improvement at 4 weeks. Gains reversed when treatment stopped.
Prospective Randomized Long-Term Study on the Efficacy and Safety of UV-Free Blue Light for Treating Mild Psoriasis Vulgaris
47 patients with mild psoriasis received 200 mW/cm^2 (group 1) or 100 mW/cm^2) group 2 UV-free blue LED treatment over 12 weeks. Patients reported high satisfaction with the results, which were statistically significant as well.
Combination 830-nm and 633-nm light-emitting diode phototherapy shows promise in the treatment of recalcitrant psoriasis: preliminary findings
Nine psoriasis patients used 633 nm red and 830 nm infrared LED therapy on recalcitrant psoriasis. The majority had failed earlier treatments. Seven patients show 60% to 100% clearance of psoriasis symptoms when measured from three to 8 months after treatment. Two of the subjects could not be located.
Psoralen-ultraviolet A treatment with Psoralen-ultraviolet B therapy in the treatment of psoriasis
Researchers treated 25 psoriasis patients with psoralen and ultraviolet-A (PUVA), and another 25 patients with psoralent and ultraviolet-B (PUVB). Psoriasis affected 25-70% of the patient’s skin. After 8 weeks of treatment, 92% of the PUVA group, and 80% of the PUVB group had remission. Limbs and trunk were more resistant than the rest of the body. 28% of PUVA and 24% of PUVB suffered erythema (redness); 32% and 28% pruitis (itchiness); 28% and 24% nausea and vomiting; 16% and 12% fever & malaise; 12% and 16% headache; 1% and 0% blister; 1% and 0% claustrophobia. Researchers concluded that PUVA and PUVB had substantially similar positive outcomes.
Ultraviolet B Phototherapy for Psoriasis: Review of Practical Guidelines
Physician’s office treatment (not a home therapy) using Narrow Band Ultraviolet B (NB-UVB) for psoriasis patients affected on greater than 10% of the body and have not responded to other treatments. UVB is dangerous without safety precautions. The doctor uses an excimer laser. The patient is treated 2x-3x per week. Is potentially combined with “emollients, calcipotriene, cortico-steroids, retinoids, and tar. NB-UVB can be used in selected patients with traditional systemic agents such as methotrexate, mycophenolate mofetil, and cyclosporine…”
The Use of a Light-Emitting Diode Device for Neck Rejuvenation and Its Safety on Thyroid Glands
30 women with no history of thyroid disease received 16 weeks of daily LED treatment in the neck area. Followup showed neck wrinkle reduction and no changes to the thyroid. This study includes only healthy participants. It does not test thyroid safety for subjects with a history of: benign thyroid disease, malignant thyroid disease, “keloid scarring, previous inflammatory or infectious skin diseases, uncontrolled medical illness, pregnancy,” or the use of growth factor-related cosmetics.
630 nm, 850 nm, 25 mW/cm2 (12.5 mW/cm^2 per color)
830 nm light-emitting diode (led) phototherapy significantly reduced return-to-play in injured university athletes: a pilot study
830 nm, 0.05 mW/cm^2, 60 J/cm^2, 1200 s relieved tendonitis
Light-emitting diode phototherapy improves muscle recovery after a damaging exercise
Effects of Light-Emitting Diode Therapy on Muscle Hypertrophy, Gene Expression, Performance, Damage, and Delayed-Onset Muscle Soreness: Case-control Study with a Pair of Identical Twins.
Reduce muscle damage, muscle pain (soreness), muscle atrophy, muscle recovery time; increase muscle mass, and athletic performance treating the quadriceps femoris muscles with 850 nm LED light with a total of 75 J.
Efficacy of low-level laser therapy in treatment of recurrent aphthous ulcers – a sham controlled, split mouth follow up study
Researchers treated 30 canker sore patients with 1 session of green light therapy.
They broke the session into four treatment sections.
The 4-part treatment significantly reduced patients’ pain and lesion size.
Treated subjects healed in 3 days on average. Sham subjects healed in 8 days.
A double-blind, placebo-controlled randomized trial evaluating the ability of low-level laser therapy to improve the appearance of cellulite
Use green 532 nm diodes without massage or mechanical manipulation to improve the appearance of cellulite in thighs and buttocks.
Researchers treated 34 women with low-energy green light.
Subjects receives three treatments a week for 2 weeks (6).
Researchers treated subjects’ hips, thighs, a waist. Treatments lasted 30 min.
Subjects had significant:
decrease in circumference of treated areas
decrease in baseline body weight
reduction in BMI
reduction in cellulite
Low-Level Laser Therapy for Reducing the Hip, Waist, and Upper Abdomen Circumference of Individuals with Obesity
Use green light therapy to reduce hip, thigh and abdomen circumference. Subject lost an average of 15.21 cm circumference after 12 sessions of low dose green light.
The effectiveness of adding low-level light therapy to minoxidil 5% solution in the treatment of patients with androgenetic alopecia
Researchers tested 785 nm (infrared) light on balding patients aged 17 to 45 years old.
The treated group received 5% minoxidil solution and infrared light therapy two times per day.
The control group received 5% minoxidil and a sham LED treatment device.
Researchers tested hair patient satisfaction, hair density and hair growth.
At 12 months, the patients getting both minoxidil and LED ligh therapy were singificantly happier with their hair growth than the sham group.
Efficacy and Safety of a Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Self-Comparison, Sham Device-Controlled Trial
Researchers applied 660 nm LED light to balding men and women over a 24 week study.
The light therapy significantly increased the hair’s coverage area.
More of the subject’s heads had hair at 24 weeks than at the beginning of the study.
The sham group saw no hair gains.
Researchers also used 650 nm red laser light, and got the same results.
The Effectiveness of Combination Therapies for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Researchers treated balding men and women aged 19 to 65 years old with 655 nm red light therapy (LLLT: low level light therapy).
They fitted helmets with 2.36 mW LED 655 nm output to administer the treatment.
They tested hair growth at 0, 8 and 16 weeks.
At the end of 16 weeks, particpants in the treatment group had more hairs and they were thicker as well.
The control group did not experience an increase in hair quanity or thickness.
There were no adverse side effects.
Effectiveness Of Low-Level Laser Therapy In Lichen Planopilaris
Researchers treated patients to low level light therapy (LLLT) using red light with a 630 nm wavelength.
All treated patients had lichen planopilaris.
Symptoms included redness (erythema), corkscrew hairs indicating too much keratin production (perifollicular hyperkeratosis), and hair loss.
After 3 and 6 months, the patients had more and thicker hair.
After 3 months, the erythema and perifollicular hyperkeratosis settled down, but after 6 months it had returned.
Lichen Planopilaris and Low-Level Light Therapy: Four Case Reports and Review of the Literature About Low-Level Light Therapy and Lichenoid Dermatosis.
Researchers reviewed four cases using red light to treat licehn planopilaris (LPP).
Using 650 nm or 660 nm light scientists reversed inflammation, LPP symptoms, and regrew natural hair.
They wrote that the patients showed “a dramatic response to LLLT [red light therapy].”
Patients experienced no adverse side effects.
Low-fluence 585 nm Q-switched Nd:YAG laser: a novel laser treatment for post-acne erythema
Green light reduced acne lesions by 67% when measured at 6 weeks past the end of the study.
Efficacy of Low-Level Laser Therapy for Body Contouring and Spot Fat Reduction
635-680 nm red light of unknown dose reduced girth at waist by 2.15 cmin men and women over 4 weeks of treatment.
Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring
Increase lymphatic system activity correlated:
- reduced wrinkles
- reduced hyperpigmentation
- enhanced rejuvenation (glow)
- increased collagen
- decreased acne
Blue and red light combination LED phototherapy for acne vulgaris in patients with skin phototype IV
Blue and red LED light treatments reduced inflammatory acne by 34% and non inflammatory acne by 78%. In addition, melanin decreased significantly, tone brightened, and texture improved.
Red light phototherapy alone is effective for acne vulgaris: randomized, single-blinded clinical trial
Treatment of acne vulgaris with a portable 630 nm to 670 nm portable LED device resulted in reduced inflammatory and non-inflammatory acne lesion counts.
Handheld LED array device in the treatment of acne vulgaris
415 combined with 633, 21 subjects, self administered handheld device over 4 weeks. Reduced lesion counts throughout study and 8 weeks post therapy, 69% reduction at 8 weeks
Non-invasive diagnostic evaluation of phototherapeutic effects of red light phototherapy of acne vulgaris
Decreased acne lesions, decreased skin sebum excretion in women at end of treatment and 3 month followup. Study used multiple wavelengths in the red range.
A study to determine the effect of combination blue (415 nm) and near-infrared (830 nm) light-emitting diode (LED) therapy for moderate acne vulgaris
Alternating 415 nm and 830 nm at each session reduced inflammatory acne lesions up to 83.3%. Non inflammatory lesions improved an average of 48.8%, but four patients had an increase. There were no side effects.
Comparison of Red and Infrared Low-level Laser Therapy in the Treatment of Acne Vulgaris
10 weeks after last treatment, group treated with 630 nm light had significant reduction in moderate acne. The 890 nm group did not have a significant reduction.
The clinical and histological effect of home‐use, combination blue–red LED phototherapy for mild‐to‐moderate acne vulgaris in Korean patients: a double‐blind, randomized controlled trial
Red and blue light two to five minute sessions for four weeks resulte in:
- inflammatory acne lesions reduced by 77%n
- oninflammatory acne lesions decreased by 54%
- reduced sebum output
- reduced inflammatory markers
- decreased sebaceous gland size
- no side effects
Home consumer red and blue LED device reduced acne lesions, sebum output, inflammatory markers and sebaceous gland size in Korean patients, with no side effects.
Randomized trial of three phototherapy methods for the treatment of acne vulgaris in Chinese patients
90% or greater acne reduction at one month using blue LED therapy on the face of Chinese patients. Some redness after treatment resolving in 2h. After 3 months, 12 of 22 patients had minimal papules and pustules, “but no nodular pustules recurred.”
Clinical comparison of salicylic acid peel and LED-Laser phototherapy for the treatment of Acne vulgaris in teenagers.
Blue and red light facial and back therapy immediately improved acne symptom better than salicylic acid treatment . “The number of comedones, papules and pustules decreased significantly at the end of the session.”
Reduction in Cholesterol and Triglyceride Serum Levels Following Low-Level Laser Irradiation: A Noncontrolled, Nonrandomized Pilot Study
Use 635 nm light to reduced triglyceride and cholesterol levels.
Effect of 635nm Low-level Laser Therapy on Upper Arm Circumference Reduction
Use 635 nm red light to reduce upper arm circumference more than 1.5 cm.
Low-Level Laser Therapy Effectiveness for Reducing Pain after Breast Augmentation
Reduce surgical pain by 37%.
Low-level laser therapy improves vision in patients with age-related macular degeneration
Improve visual acuity in cataract and healthy eyes; reduce metamophosia, scotoma, and dyschromatopsia; reduced wet AMD edma and bleeding; for at least 3-6 mo. post treatment.
Low-Level Laser-Assisted Liposuction: A 2004 Clinical Study of its Effectiveness for Enhancing Ease of Liposuction Procedures and Facilitating the Recovery Process for Patients Undergoing Thigh, Hip, and Stomach Contouring
Emulsify fat before liposuction extraction.
Efficacy and safety of long pulse 1064 and 2940 nm lasers in noninvasive lipolysis and skin tightening
Reduce waist circumference and total body fat, decreased fat thickness, and improve skin stiffness.
Light Modulates Leptin and Ghrelin in Sleep-Restricted Adults
Reduce sleep-deprivation hunger using red light to increase leptin and reduce ghrelin.
Effects of low-level laser therapy (LLLT 808 nm) on lower limb spastic muscle activity in chronic stroke patients
Use 808 nm on weak leg of stroke patient with muscle spacicity to decrease pain, increase time to muscle fatigue onset, and increase peak torque.
Assessing the Therapeutic Effect of 630 nm Light-Emitting Diodes Irradiation on the Recovery of Exercise-Induced Hand Muscle Fatigue with Surface Electromyogram
Decrease muscle fatigue using 630 nm LED irradiation.
A controlled trial to determine the efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase
Reduce wrinkles, increase collagen
Optically improved mitochondrial function redeems aged human visual decline
Improve blue contrast vision in adults over 40 years old.
Regulation of Skin Collagen Metabolism In Vitro Using a Pulsed 660 nm LED Light Source: Clinical Correlation with a Single-Blinded Study
Reverse collagen downregulation and MMP-1 upregulation, decreasing wrinkles, and increasing collagen.
Transcranial Photobiomodulation Therapy in the Cognitive Rehabilitation of Patients with Cranioencephalic Trauma
Improvements in immediate recall, information processing speed, verbal learning, PTSD stress reduction, depression reduction, reduced headache, improved sleep, and many more benefits.
Nutritional Ketosis and photobiomodulation remediate mitochondria warding off Alzheimer’s disease in a diabetic, ApoE4+ patient with mild cognitive impairment: A case report
Ketogenic diet and PBM restore cognition, increase insulin sensitivity, improve metabolic flexibilityin diabetic, ApoE4 heterozygous individual.
Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function, Cerebral Perfusion, and Resting-State Functional Connectivity in Patients With Dementia: A Pilot Trial
Intranasal and transcranial application of 810 nm improved memory, cognition and MRI results in Alzheimer’s patients.
Rapid Reversal of Cognitive Decline, Olfactory Dysfunction, and Quality of Life Using Multi-Modality Photobiomodulation Therapy: Case Report.
Alzheimer’s patient treatment: Improve cognitive and memory scores; regain sense of smell; reduce stress in patient and caregiver.
The Effect of Light-Emitting Diode (590/830 Nm)-Based Low-Level Laser Therapy on Posttraumatic Edema of Facial Bone Fracture Patients
16.5% edema reduction in LLLT group compared to 7.3% in sham group.
Effects of Low-Level Laser Therapy (LLLT) in the Development of Exercise-Induced Skeletal Muscle Fatigue and Changes in Biochemical Markers Related to Postexercise Recovery
Increase voluntary elbow flexion repetitions before exhaustion.
Efficacy of High Intensity Laser Therapy in the Treatment of Male With Osteopenia or Osteoporosis: A Randomized Placebo-Controlled Trial
Decrease pain and fall risk in men with osteopenia.
Therapeutic Outcomes of Low-Level Laser Therapy for Closed Bone Fracture in the Human Wrist and Hand
Reduce pain and improve healing of wrist and hand closed bone fractures.
Improved Cognitive Function After Transcranial, Light-Emitting Diode Treatments in Chronic, Traumatic Brain Injury: Two Case Reports
Improve cognition and memory in chronic TBI patients.
The clinical efficacy of low-power laser therapy on pain and function in cervical osteoarthritis.
Reduce neck osteoarthritis pain.
Lasertherapy efficacy in temporomandibular disorders: control study.
Decrease TMJ pain and increase jaw movement.
Evaluation of low-level laser therapy in the treatment of temporomandibular disorders.
Improve TMJ mouth opening range, decrease pain, chewing difficulty, and tenderness.
The effect of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial.
Improve knee osteoarthritis pain, flexion, pressure, sensitivity, and circumference.
Efficacy of different therapy regimes of low‐power laser in painful osteoarthritis of the knee: A double‐blind and randomized‐controlled trial
Reduce knee osteoarthritis pain.
Improvement of Pain and Disability in Elderly Patients with Degenerative Osteoarthritis of the Knee Treated with Narrow‐Band Light Therapy
Reduce geriatric degenerative osteoarthritis pain.
Reduction of Subcutaneous Fat and Improvement in Cellulite Appearance by Dual-Wavelength, Low-Level Laser Energy Combined With Vacuum and Massage
Reduce thigh fat and circumference.
The Growth of Human Scalp Hair in Females Using Visible Red Light Laser and LED Sources
Increase female scalp hair count.
Photobiomodulation via a Cluster Device Associated With a Physical Exercise Program in the Level of Pain and Muscle Strength in Middle-Aged and Older Women With Knee Osteoarthritis: A Randomized Placebo-Controlled Trial
Reduce knee arthritis pain and inflammation.
Incorporation of Photobiomodulation Therapy Into a Therapeutic Exercise Program for Knee Osteoarthritis: A Placebo-Controlled, Randomized, Clinical Trial
Reduce knee osteoarthritis pain.
Can Photobiomodulation Associated With Implantation of Mesenchymal Adipose-Derived Stem Cells Attenuate the Expression of MMPs and Decrease Degradation of Type II Collagen in an Experimental Model of Osteoarthritis?
Prevent knee arthritis inflammation and degeneration.
Comparison between cold water immersion therapy (CWIT) and light emitting diode therapy (LEDT) in short-term skeletal muscle recovery after high-intensity exercise in athletes—preliminary results
Reduce post-exercise lactate and creatine kinase, known to be consistent with faster exercise recovery.
Effect of Light-Emitting Diodes Therapy (LEDT) on Knee Extensor Muscle Fatigue
Reduce post-exercise loss of function.
A randomised, placebo controlled trial of low level laser therapy for activated Achilles tendinitis with microdialysis measurement of peritendinous prostaglandin E2 concentrations
Reduce Achilles tendinitis pain and inflammation.
The Effectiveness of Therapeutic Class IV (10 W) Laser Treatment for Epicondylitis
Improve tendonitis functionality, increase strength, decrease pain, and improve extension in tendinitis
TREATMENT OF POST HERPETIC NEURALGIA USING A 904 nm (INFRARED) LOW INCIDENT ENERGY LASER: A CLINICAL STUDY
Reduce post-herpetic neuralgia pain from from 8.54/10 to 0-3/10.
Early Application of Low-Level Laser May Reduce the Incidence of Postherpetic Neuralgia (PHN)
Prevent post-herpetic neuralgia: “Applying LLLT within the first 5 days of herpes zoster eruption significantly reduced the incidence of PHN.”
LLLT: low level light therapy
PHN: post-herpetic neuralgia
Role of Low-Level Laser Therapy in Post-Herpetic Neuralgia: A Pilot Study
Reduce shingles pain from severe to severe/moderate/mild with no remissions for at least “several months.”
Low-intensity Laser Therapy Is an Effective Treatment for Recurrent Herpes Simplex Infection. Results From a Randomized Double-Blind Placebo-Controlled Study
Increase time to recurrence of herpes outbreak.
Effect of Laser Phototherapy on Recurring Herpes Labialis Prevention: An in Vivo Study
780 nm, 60 mW, 3 J/cm^2 (50 s) or 4.5 J/cm^2 (75 s), 2x/week/10 weeks (20) reduced herpes pain and lesion size.
Recurrent Herpes Simplex Infections: Laser Therapy as a Potential Tool for Long-Term Successful Treatment
660 nm, 100 mW, 8 s, 12 points/5 sessions (60 applications) per point , 30 J/cm^2 encouraged herpes remission for at least 17 months.
The Effect of 670-nm Low Laser Therapy on Herpes Simplex Type 1
Reduce outbreak length and increase time between herpes outbreaks.
Laser Acupuncture Reduces Body Fat in Obese Female Undergraduate Students
Reduce body mass index, body fat mass, waist girth, hip girth, and wast to hip ratio.
Impact of Low Level Laser Therapy on Skin Blood Flow
Increase skin blood flow.
Low-level Laser Treatment With Near-Infrared Light Increases Venous Nitric Oxide Levels Acutely: A Single-Blind, Randomized Clinical Trial of Efficacy
890 nm, 636 mW/cm^2, 60 s, 300s, 900 s, increased blood nitric oxide
Randomized, Double-Blind, and Placebo-Controlled Clinic Report of Intranasal Low-Intensity Laser Therapy on Vascular Diseases
Lower total cholesterol and increase HDL-c.
Effects of 780 Nm Diode Laser Irradiation on Blood Microcirculation: Preliminary Findings on Time-Dependent T1-weighted Contrast-Enhanced Magnetic Resonance Imaging (MRI)
Reduce wound pain and increase blood flow.
Immediate Effects of Monochromatic Infrared Energy on Microcirculation in Healthy Subjects
Increase capillary blood cell velosity and superficial skin blood flow.
The Effect of LED on Blood Microcirculation During Chronic Wound Healing in Diabetic and Non-Diabetic Patients-A Prospective, Double-Blind Randomized Study
Heal chronic wounds in both diabetics and non-diabetics.
Blood Pressure Controlled by Low Reactive Level Diode Laser Therapy (LLLT)
Significant reduction in hypertension to healthy measurements in some cases.
The Effects of Transcranial LED Therapy (TCLT) on Cerebral Blood Flow in the Elderly Women
Increase cerebral artery blood floow, decrease resistance.
Effect of Low Level Laser Therapy in Rheumatoid Arthritis Patients With Carpal Tunnel Syndrome
Decrease wrist pain and increase wrist functionality in carpal tunnel patients who have rheumatoid arthritis.
The Effectiveness of Conservative Treatments of Carpal Tunnel Syndrome: Splinting, Ultrasound, and Low-Level Laser Therapies
Decrease carpal tunnel pain.
Comparison of Splinting and Splinting Plus Low-Level Laser Therapy in Idiopathic Carpal Tunnel Syndrome
Increase carpal tunnel strength and mobility.
Comparison of the Long-Term Effectiveness of Physiotherapy Programs With Low-Level Laser Therapy and Pulsed Magnetic Field in Patients With Carpal Tunnel Syndrome
Decrease carpal tunnel pain.
Placebo-controlled Investigation of Low-Level Laser Therapy to Treat Carpal Tunnel Syndrome
Reduce carpal tunnel pain, increase meridian nerve conduction in carpal tunnel wrists.
Low-level Laser Therapy With a Wrist Splint to Treat Carpal Tunnel Syndrome: A Double-Blinded Randomized Controlled Trial
Increase hand grip strength in carpal tunnel wrists.
A New Treatment Protocol Using Photobiomodulation and Muscle/Bone/Joint Recovery Techniques Having a Dramatic Effect on a Stroke Patient’s Recovery: A New Weapon for Clinicians
Decrease stroke defecits.
N=1 significant stroke symptom improvements in:
- severe diziness
- non-functional left hand
- severe right hand spasticity
- right lateral sixth nerve palsy
- unable to walk
Multi-Watt Near-Infrared Phototherapy for the Treatment of Comorbid Depression: An Open-Label Single-Arm Study
Reduce depression symptoms including sucidal ideation.
A Case Control Series for the Effect of Photobiomodulation in Patients With Low Back Pain and Concurrent Depression
Reduce back pain and depression.
Cognitive Enhancement by Transcranial Laser Stimulation and Acute Aerobic Exercise
Improve vigilance task and working memory scores similar to that seen with 20 minutes of aerobic exercise.
Acute Effects of Near Infrared Light Therapy on Brain State in Healthy Subjects as Quantified by qEEG Measures
Decrease physical reaction times in concussion patients.
Beneficial Neurocognitive Effects of Transcranial Laser in Older Adults
Improve memory and increase brain blood oxygen in patients at risk for cognitive decline.
Transcranial Photobiomodulation to Augment Lithium in Bipolar-I Disorder
830 nm, 332 mW/cm^2,120 s, 40 J/cm^2, unknown targets, 8 treatments, unknown schedule, reduced anhedonia apathy, increased libido, decreased anxiety, decreased irritability, decreased impulsivity, improved sleep
Psychological Benefits 2 and 4 Weeks After a Single Treatment With Near Infrared Light to the Forehead: A Pilot Study of 10 Patients With Major Depression and Anxiety
Decrease depression and anxiety in TBI patients.
APPLICATION OF LOW REACTIVE-LEVEL LASER THERAPY (LLLT) IN PATIENTS WITH CEREBRAL PALSY OF THE ADULT TENSION ATHETOSIS TYPE
830 nm, 60 mW/cm^2, 30 s/site, 900 s-1800 s total, 1.8 J/cm^2, myotonic face and neck sites, 1x/week/2 weeks, or 1/month, up to 18 months increased ability to voluntarily move, significantly reduced (scores 10 to score 3) back and neck pain, reduced involuntary athetoic (slow writhing), increased motor function in limbs, trunk, vocalization, increased ability to chew and swallow, decreased dysuria (painful urination), and decreased breathing problems.
Focal Increase in Cerebral Blood Flow After Treatment With Near-Infrared Light to the Forehead in a Patient in a Persistent Vegetative State
830 nm, 11.4 mW/cm^2, 1800 s, 2/day/73 days (146) improved blood flow and correlated with patient regaining cognition.
“The patient showed some improvement in his neurological condition by moving his left arm/hand to reach the tracheostomy tube, post-LED therapy.”
Transcranial Photobiomodulation With Near-Infrared Light for Generalized Anxiety Disorder: A Pilot Study
In Generalized Anxiety Disorder (GAD patients):
- reduce Hamilton Anxiety Scale (SIGH-A) score
- reduce Clinical Global Impressions-Severity (OGI-S) subscale score
- Increase Pittsburgh Sleep Quality Index (PSQI subscale score
Use of low-energy laser as adjunct treatment of alcohol addiction
Improve beta endorphin plasma concentration and Beck Depression Inventory Fast Screen score in alcoholics seeking help quitting.
Effects of red light on sleep inertia
Reduce morning sleepiness known as “sleep inertia” without reducing melatonin.
Is light-emitting diode phototherapy (LED-LLLT) really effective?
Clear treatment-resistant contact dermatitis that started after alpha-hydroxy acid (AHA) peel compound application.
Oxidative Stress in Muscle Diseases: Current and Future Therapy 2019
Ddecrease post-exercise stress on 10 data points
Red light-promoted skin barrier recovery: Spatiotemporal evaluation by transepidermal potential
Promoted recovery of wound epidermal barrier.
Infrared and skin: Friend or foe
Infrared Affect on Skin Review Rationale
Photobiomodulation researchers examined near infrared (NIR) studies that had resulted in damaged skin. The researchers determined that near infrared caused damage when applied in strong doses. Low dose NIR spread over time reduces wrinkles, produces collagen, and causes no harm.
Infrared Affect on Skin Review Hypothesis
Previous studies found near infrared photobiomodulation (PBM) damage because the doses were too high.
Infrared Affect on Skin Study Method
Examine PBM studies that showed near infrared light skin damage to correlate light doses with skin damage.
Infrared Affect on Skin Study Summary
In a review of Near Infrared photobiomodulation (PBM), use of near infrared light only caused damage when the dose was too high.
Near infrared light between 760 and 1,400 nm wavelengths rejeuvanates skin when applied in low (but not too low!) doses over time.
For more collagen and fewer wrinkles, use any of these wavelengths as frequently as once per day, at a dose of 20 to 50 mW/cm^2.
- 600 nm
- 805 nm
- 830 nm
- 900 nm
Infrared Review of Skin Effects Study Conclusion
- Ultraviolet (UV) and some infrared light frequencies are always harmful to the skin
- Near infrared with wavelengths between 760 nm and 1,400 nm are healthy when administered in a dose of 50 mW/cm^2 using any of these wavelengths: 660 nm, 805 nm, 830 nm, or 900 nm
- Wavelengths mentioned in the previous bullet point induce more collagen and elastin; result in better skin tone and fewer wrinkles.
- Use no more than 50 mW/cm^2, once a day or less.
“The body will absorb only so much energy before that energy damages the cytochrome cells.”
In every study reviewed, IR-A induced damage when the total energy absorbed was higher than one would receive from morning or evening sun.
Sunlight infrared is healthy when the shadows in the morning and evening, when the shadows are long. Noontime infrared creates oxidative stress. To get healthy artficial infrared light, use no more than 50 mW/cm^2 of 660 nm, 805 nm, or 830 nm wavelength light.
EMF Channel Remarks on Infrared Review Publication
NIR frequencies can penetrate epidermis, dermis, and subcutaneous tissue.
To visualize what this means, the NIR light reaches all of this:
- epidermis: immune system and pigment cells
- dermis: hair follicles, nerve endings, sweat glands, oil
- subcutaneous tissue: connective tissue, fat, blood vessels
You can’t see infrared light. If you can feel it as heat, you’re getting too much.
Interestingly, if you use a high dose but simultaneously cool the skin, you can prevent thermal damage.
But this method isn’t tested for creating a healthy response. We just know that it prevents damage, not if it creates collagen and smoother skin.
About the EMF Channel Light Dose Database
Many people purchase red light therapy or neuromuscular electrical stimulation devices without knowing optimal doses for the results they want to see. The right dose is especially key to light therapies, which have optimal windows of wavelength and energy delivered. Treatment doses outside of those windows will nullify results or harm the user. I took the results from successful EMF studies when these studies included:
- Photobiomodulation (Red Light Therapy, Blue Light Therapy, Low Level Light Therapy)
- Transcutaneous Electromagnetic Nerve Stimulation (TENS)
- Pulsed Electromagnetic Field (PEMF) Therapy
- Neuromuscular Electrical Stimulation (NMES)
Many studies do not report exact dose parameters they used. They are therefore not included here, even the study reported a therapeutic result.
Source: Turchin, Curtis. Light and Laser Therapy: Clinical Procedures 6th Edition (p. 16)