Sleep Deprivation Hunger Hormone Correction Red Light Dose

chronic sleep deprivation reduces leptin, increases ghrelin
less leptin = more hunger
more ghrelin = more hunger
8 hours sleep vs 5 hours sleep
60 lux 633 nm
532 nm green
475 nm blue
morning dim light
dim light, 5 hour sleep, reduced leptin concentrations
dim light, 8 hour sleep, did not reduce leptin concentrations
red light, 5 hour sleep increased leptin compared to 5 hour dim light
green light, 5 hour sleep, increased leptin compared to 5 hour dim light
blue light, 5 hour sleep, increased leptin compared to 5 hour dim light
red light, 5 hour sleep, decreased ghrelin
green light, 5 hour sleep, decreased ghrelin
blue light, 5 hour sleep, did not decrease ghrelin

FOUR CONDITIONS two hours upon wakening
1 red light, 60 lux, 0.325 W/m2, peak 633 nm, full-width-half-maximum [FWHM] = 14 nm
2 green light, 60 lux, 0.105 W/m2, peak = 532 nm, FWHM=34 nm
3 blue light, 60 lux, 0.585 W/m2, peak = 475 nm, FWHM = 21 nm
4 dim light, 0.5 lux at the eye of 630 nm red light

RED 0.325 W/m^2 = 0.000325 mW/cm^2
0.325 W/m^2 x 7200 s = 2,340 J

two LED on goggles

9 weeks
8 hour sleep baseline
weeks 3 5 7 9 5 hour sleep

2 hour exposure on waking

LEPTIN
8 hour dim 7.9 median ng/mL
5 hour dim 6.2
5 hour green 8.4
5 hour blue 9.1
5 hour red 9.8

GHRELIN
8 hour dim 945
5 hour dim 957
5 hour green 847
5 hour blue 884
5 hour red 768